ISSN 1662-4009 (online)

ey0018.5-6 | Advances in clinical practice | ESPEYB18

5.6. Vitamin D supplements for prevention of tuberculosis infection and disease

Ganmaa Davaasambuu , Uyanga Buyanjargal , Zhou Xin , Gantsetseg Garmaa , Delgerekh Baigali , Enkhmaa Davaasambuu , Khulan Dorjnamjil , Ariunzaya Saranjav , Sumiya Erdenebaatar , Bolortuya Batbileg , Yanjmaa Jutmaan , Enkhtsetseg Tserenkhuu , Munkhzaya Ankhbat , Tunsag Murneren , Khudyakov Polyna , Seddon James A , Marais Ben J , Batbayar Ochirbat , Erdenetuya Ganbaatar , Amarsaikhan Bazarsaikhan , Spiegelman Donna , Tsolmo Jadambaa , Martineau Adrian R

N Engl J Med 2020; 383:359–368 DOI: 10.1056/NEJMoa1915176 Abstract: https://pubmed.ncbi.nlm.nih.gov/32706534/In brief: Vitamin D metabolites support innate immune responses to Mycobacterium tuberculosis. In this phase 3, randomized, controlled trial of vitamin D supplementation to prevent tuberculosis infection, there was no reduction of risk of tuberculosis infection, tubercu...